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What is ProPhexel®? Examining a Patented Sleep & Recovery Catalyst

February 16, 2026

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You know that feeling when you’re reading a supplement label, and you stumble across an ingredient with a registered trademark symbol that you’ve never seen before?

Maybe you squint. Maybe you shrug. Maybe you think, “Is this real science or just marketing in a lab coat?”

Fair question. You should be skeptical. I would be.

So, let’s talk about ProPhexel®—the proprietary compound you’ll find in DISCONNEKT®. What is it? Where did it come from? Does it actually do anything, or is it just fancy packaging?

Pull up a chair. We’re going deep.

First Things First: What IS ProPhexel®?

ProPhexel® is a patented, multi-herbal sleep and recovery catalyst developed by All American Pharmaceutical. It’s one of the key ingredients that make DISCONNEKT different from the run-of-the-mill sleep aids you’ll find on drugstore shelves.

But here’s what matters: it’s not just one thing. It’s a proprietary blend of three traditional sleep-supporting herbs, each with its own scientific pedigree:

  • Valerian (Valeriana officinalis) extract (root)
  • Chamomile (Matricaria chamomilla) extract (flower)
  • Passionflower (Passiflora incarnata) extract (aerial parts)

When you see “50mg ProPhexel®” on the DISCONNEKT label, that’s what you’re getting—a precise, patent-protected combination of these three botanical extracts, formulated to work synergistically.

Why “Proprietary” Doesn’t Mean “Fake”

I know. The supplement industry has given “proprietary blends” a bad reputation. Some companies hide behind them to mask underdosed ingredients.

That’s not what’s happening here.

ProPhexel® is protected by US Patent 12,029,762 and 11,376,282. That means the specific combination, the extraction methods, and the intended use have been reviewed and granted patent protection by the United States Patent and Trademark Office.

Patents aren’t easy to get. They require demonstrating that something is novel, non-obvious, and useful. The USPTO doesn’t just hand them out because you asked nicely.

So when you see those patent numbers, you’re looking at a government-issued stamp that says, “This is real, and it’s ours.”

Meet the Trio: What’s Actually in ProPhexel®

Let’s break down each component so you know what you’re putting in your body.

Valerian Root: The Ancient Sleep Ally

Valerian has been used since ancient Greece and Rome to promote calmness and sleep. Hippocrates wrote about it. The name comes from the Latin valere, meaning “to be strong” or “to be healthy.”

How it works: Valerian increases the availability of GABA (gamma-aminobutyric acid) in the brain. GABA is your brain’s primary inhibitory neurotransmitter—it’s the “off switch” for neuronal excitability. More GABA available means your nervous system receives the signal to calm down.

The science: Research shows valerian can reduce the time it takes to fall asleep and improve sleep quality, particularly in people with mild insomnia. It doesn’t sedate you like prescription sleep aids. It just helps your brain find its natural off-ramp to sleep.

Chamomile: Nature’s Gentle Nudge

Chamomile is probably the most recognized sleep herb on the planet. Your grandmother drank it. Your grandmother’s grandmother probably drank it too.

How it works: Chamomile contains apigenin, an antioxidant that binds to specific receptors in your brain that promote sleepiness and reduce anxiety. Think of it as a gentle key turning a lock that says, “Maybe it’s time to wind down now.”

The science: Clinical studies have shown that chamomile extract can significantly improve sleep quality and reduce anxiety symptoms. It’s not a hammer. It’s a whisper. But sometimes a whisper is exactly what your buzzing brain needs.

Passionflower: The GABA Booster

Passionflower might sound like something from a hippie tea shop, but don’t let the name fool you. This plant has solid scientific backing.

How it works: Like valerian, passionflower has been shown to increase GABA levels in the brain. But it may work through slightly different pathways, which is why combining them makes sense.

The science: Studies on passionflower extract demonstrate significant improvements in sleep quality and duration. Some research suggests it may be particularly effective for people whose sleep issues are tied to racing thoughts and anxiety.

The Synergy Question: Why Combine Them?

Here’s where it gets interesting.

Each of these herbs works, but they work through slightly different mechanisms. Valerian boosts GABA availability. Chamomile binds to benzodiazepine receptors. Passionflower influences GABA through its own pathways.

When you combine them, you’re not just adding effects—you’re potentially creating synergy. The whole becomes greater than the sum of its parts.

Think of it like a team:

  • Valerian is the strong, reliable veteran
  • Chamomile is the gentle, consistent presence
  • Passionflower is the specialist who covers different ground

Together, they create a multi-targeted approach to helping your nervous system find calm.

That’s the philosophy behind ProPhexel®—and honestly, behind DISCONNEKT as a whole. You don’t just need one “off switch.” You need a system.

The Patent Story: What It Means for You

Let’s talk about those patent numbers: US Patent 12,029,762 and 11,376,282.

A patent means someone—in this case, All American Pharmaceutical—did the work to develop a specific formulation and then proved to the government that it was worth protecting.

What does that mean for you?

It means consistency. When you see ProPhexel® on a label, you know you’re getting the exact same proprietary blend every single time. Not a “roughly similar” mix. Not a “close enough” substitute. The real thing.

It means accountability. Patent holders have a vested interest in maintaining quality and efficacy. Their reputation—and their intellectual property—depends on it.

It means innovation. Patents exist to encourage companies to invest in research and development. Without patent protection, why would anyone spend years developing a novel formulation? They wouldn’t. They’d just copy someone else’s work.

How ProPhexel® Fits Into DISCONNEKT

ProPhexel® doesn’t work alone in DISCONNEKT. It’s part of a broader strategy:

IngredientRole
ProPhexel® (50mg)Multi-herbal blend targeting GABA pathways and calming the nervous system
GABA (50mg)Direct neurotransmitter support—the brain’s natural “off switch”
TryptoLyn™ (50mg)Buffered L-Tryptophan—precursor to serotonin and melatonin
TheanaLyn™ (5mg)Buffered L-Theanine—promotes alpha brain waves for relaxed focus
Melatonin (5mg)Master sleep hormone—regulates the sleep-wake cycle

Think of it as a coordinated campaign against stimulant-driven wakefulness. ProPhexel® is one of the key players, but it works best when supported by the rest of the team.

The Bottom Line on ProPhexel®

So, what is ProPhexel®?

It’s science, not marketing.

It’s three traditional herbs, combined in a proprietary, patented formulation designed to do one thing: help your nervous system find calm when stimulants are telling it to stay fired up.

It’s not a sedative. It’s not a knockout punch. It’s a catalyst that helps your body’s natural sleep mechanisms function as they’re supposed to.

When you take DISCONNEKT 15-20 minutes before bed, ProPhexel® is part of the reason you can actually power down after an evening workout. It’s part of the reason you can wake up ready to train again, rather than feeling groggy and dragging.

And honestly? That’s the whole point.

Frequently Asked Questions

Is ProPhexel® just a marketing gimmick?

No. It’s a patented, proprietary blend with real ingredients and actual USPTO patent protection. The patent numbers (12,029,762 and 11,376,282) are right on the label.

Can I just take valerian, chamomile, and passionflower separately?

You could. But you’d be guessing at ratios, quality, and consistency. ProPhexel® takes the guesswork out by delivering a precise, standardized blend that’s been developed specifically for this purpose.

Does ProPhexel® work on its own?

In DISCONNEKT, it works as part of a complete formulation with GABA, melatonin, TryptoLyn™, and TheanaLyn™. These ingredients are designed to work together synergistically.

Is ProPhexel® safe?

ProPhexel® contains herbs with centuries of traditional use and modern scientific support. As with any supplement, follow the recommended use and consult your physician if you have specific health concerns or are taking medications.

Why is it called a “catalyst”?

Because it helps facilitate the body’s natural sleep processes rather than forcing sedation. It’s not knocking you out; it’s helping your body find its own way to sleep.

References

  1. EFX Sports. DISCONNEKT product label.
  2. EFX Sports. DISCONNEKT product webpage.
  3. United States Patent and Trademark Office. US Patent 12,029,762 and 11,376,282.
  4. Sahin K, Gencoglu H, Korkusuz AK, et al. (2024). Impact of a Novel Valerian Extract on Sleep Quality, Relaxation, and GABA/Serotonin Receptor Activity in a Murine Model. Antioxidants (Basel). 13(6):657.
  5. Bruni O, Ferini-Strambi L, Giacomoni E, Pellegrino P. (2021). Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep. Nutrients. 13(2):530.
  6. Amsterdam JD, Li Y, Soeller I, et al. (2009). A Randomized, Double-Blind, Placebo-Controlled Trial of Oral Matricaria Recutita (Chamomile) Extract Therapy for Generalized Anxiety Disorder. J Clin Psychopharmacol. 29(4):378-82.
  7. Hanrahan JR, Chebib M, Johnston GA. (2011). Flavonoid modulation of GABA(A) receptors. Br J Pharmacol. 163(2):234-45.
  8. Janda K, Wojtkowska K, Jakubczyk K, et al. (2024). Passiflora incarnata as an Adjunctive Treatment for Anxiety and Sleep Disorders. Quality in Sport. 35:56361.
  9. Lelli D, Sahebkar A, Johnston TP, Pedone C. (2021). Use of Plant-Derived Natural Products in Sleep Disturbances. Adv Exp Med Biol. 1308:217-224.
  10. Meolie AL, Rosen C, Kristo D, et al. (2005). Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence. J Clin Sleep Med. 1(2):173-87.
  11. Larzelere MM, Wiseman P. (2002). Anxiety, depression, and insomnia. Prim Care. 29(2):339-60, vii.

Brian Andrews

Brian Andrews is the President and Co-founder of EFX Sports, a leader in 3X tested, scientifically formulated supplements. A dedicated advocate for informed fitness, Brian co-hosted the EFX Sports Show on ESPN 910 and has authored multiple industry-defining books, including Creatine: Industry Insider Secrets Revealed and Formulated to Win.

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